{
  "id": "cond-mat/0202054",
  "version": "v1",
  "published": "2002-02-04T17:20:09.000Z",
  "updated": "2002-02-04T17:20:09.000Z",
  "title": "Punctuated evolution for the quasispecies model",
  "authors": [
    "Joachim Krug",
    "Christian Karl"
  ],
  "journal": "Physica A 318 (2003) 137-143",
  "doi": "10.1016/S0378-4371(02)01417-6",
  "categories": [
    "cond-mat.stat-mech",
    "cond-mat.dis-nn",
    "q-bio"
  ],
  "abstract": "Biological evolution in a sequence space with random fitnesses is studied within Eigen's quasispecies model. A strong selection limit is employed, in which the population resides at a single sequence at all times. Evolutionary trajectories start at a randomly chosen sequence and proceed to the global fitness maximum through a small number of intermittent jumps. The distribution of the total evolution time displays a universal power law tail with exponent -2. Simulations show that the evolutionary dynamics is very well represented by a simplified shell model, in which the sub-populations at local fitness maxima grow independently. The shell model allows for highly efficient simulations, and provides a simple geometric picture of the evolutionary trajectories.",
  "revisions": [
    {
      "version": "v1",
      "updated": "2002-02-04T17:20:09.000Z"
    }
  ],
  "analyses": {
    "keywords": [
      "quasispecies model",
      "punctuated evolution",
      "universal power law tail",
      "shell model",
      "total evolution time displays"
    ],
    "tags": [
      "journal article"
    ],
    "note": {
      "typesetting": "TeX",
      "pages": 0,
      "language": "en",
      "license": "arXiv",
      "status": "editable"
    }
  }
}