{ "id": "2104.03454", "version": "v1", "published": "2021-04-08T01:23:04.000Z", "updated": "2021-04-08T01:23:04.000Z", "title": "Analysis of Mass-Action Systems by Split Network Translation", "authors": [ "Matthew D. Johnston" ], "categories": [ "math.DS", "math.OC" ], "abstract": "We introduce the notion of corresponding a chemical reaction network to a split network translation, and use this novel process to extend the scope of existing network-based theory for characterizing the steady state set of mass-action systems. In the process of network splitting, the reactions of a network are divided into subnetworks, called slices, in such a way that, when summed across the slices, the stoichiometry of each reaction sums to that of the original network. This can produce a network with more desirable structural properties, such as weak reversibility and a lower deficiency, which can then be used to establish steady state properties of the original mass-action system such as multistationarity and absolute concentration robustness. We also present a computational implementation utilizing mixed-integer linear programming for determining whether a given chemical reaction network has a weakly reversible split network translation.", "revisions": [ { "version": "v1", "updated": "2021-04-08T01:23:04.000Z" } ], "analyses": { "subjects": [ "92C42", "34A34" ], "keywords": [ "mass-action system", "reversible split network translation", "chemical reaction network", "utilizing mixed-integer linear programming", "computational implementation utilizing mixed-integer linear" ], "note": { "typesetting": "TeX", "pages": 0, "language": "en", "license": "arXiv", "status": "editable" } } }