{ "id": "2003.14092", "version": "v1", "published": "2020-03-31T11:00:17.000Z", "updated": "2020-03-31T11:00:17.000Z", "title": "Moran model with strong selection and $Λ$-Wright-Fisher SDE", "authors": [ "François Gaston Ged" ], "comment": "21 pages", "categories": [ "math.PR" ], "abstract": "We study a population model of fixed size undergoing strong selection where individuals accumulate beneficial mutations, namely the Moran model with selection. In a specific setting with strong selection, Schweinsberg showed that the genealogy of the population is described by the so-called Bolthausen-Sznitman's coalescent. In this paper we sophisticate the model by splitting the population into two adversarial subgroups, that can be interpreted as two different alleles, one of which has a selective advantage over the other. We show that the proportion of disadvantaged individuals converges to the solution of a stochastic differential equation (SDE) as the population's size goes to infinity, named the $\\Lambda$-Wright-Fisher SDE with selection. This stochastic differential equation already appeared in the $\\Lambda$-lookdown model with selection studied by Bah and Pardoux, in the case where the population's genealogy is described by Bolthausen-Sznitman's coalescent.", "revisions": [ { "version": "v1", "updated": "2020-03-31T11:00:17.000Z" } ], "analyses": { "subjects": [ "60J80", "92D15", "92D25", "60H10" ], "keywords": [ "moran model", "wright-fisher sde", "size undergoing strong selection", "stochastic differential equation", "individuals accumulate beneficial mutations" ], "note": { "typesetting": "TeX", "pages": 21, "language": "en", "license": "arXiv", "status": "editable" } } }