{
  "id": "1908.09374",
  "version": "v1",
  "published": "2019-08-25T19:10:24.000Z",
  "updated": "2019-08-25T19:10:24.000Z",
  "title": "Direct visualization of charge transport in suspended (or free-standing) DNA strands by low-energy electron microscopy",
  "authors": [
    "Tatiana Latychevskaia",
    "Conrad Escher",
    "William Andregg",
    "Michael Andregg",
    "Hans-Werner Fink"
  ],
  "journal": "Scientific Reports 9, 8889 (2019)",
  "doi": "10.1038/s41598-019-45351-4",
  "categories": [
    "cond-mat.mes-hall",
    "physics.bio-ph",
    "physics.ins-det"
  ],
  "abstract": "Low-energy electrons offer a unique possibility for long exposure imaging of individual biomolecules without significant radiation damage. In addition, low-energy electrons exhibit high sensitivity to local potentials and thus can be employed for imaging charges as small as a fraction of one elementary charge. The combination of these properties makes low-energy electrons an exciting tool for imaging charge transport in individual biomolecules. Here we demonstrate the imaging of individual deoxyribonucleic acid (DNA) molecules at the resolution of about 1 nm with simultaneous imaging of the charging of the DNA molecules that is of the order of less than one elementary charge per nanometer. The cross-correlation analysis performed on different sections of the DNA network reveals that the charge redistribution between the two regions is correlated. Thus, low-energy electron microscopy is capable to provide simultaneous imaging of macromolecular structure and its charge distribution which can be beneficial for imaging and constructing nano-bio-sensors.",
  "revisions": [
    {
      "version": "v1",
      "updated": "2019-08-25T19:10:24.000Z"
    }
  ],
  "analyses": {
    "keywords": [
      "low-energy electron microscopy",
      "charge transport",
      "direct visualization",
      "dna strands",
      "elementary charge"
    ],
    "tags": [
      "journal article"
    ],
    "publication": {
      "publisher": "Nature"
    },
    "note": {
      "typesetting": "TeX",
      "pages": 0,
      "language": "en",
      "license": "arXiv",
      "status": "editable"
    }
  }
}