{ "id": "1703.03799", "version": "v1", "published": "2017-03-10T18:56:09.000Z", "updated": "2017-03-10T18:56:09.000Z", "title": "DNA Origami and Unknotted A-trails in Torus Graphs", "authors": [ "Ada Morse", "William Adkisson", "Jessica Greene", "David Perry", "Brenna Smith", "Jo Ellis-Monaghan", "Greta Pangborn" ], "comment": "23 pages, 20 figures", "categories": [ "math.CO" ], "abstract": "Motivated by the problem of determining unknotted routes for the scaffolding strand in DNA origami self-assembly, we examine existence and knottedness of A-trails in graphs embedded on the torus. We show that any A-trail in a checkerboard-colorable torus graph is unknotted and characterize the existence of A-trails in checkerboard-colorable torus graphs in terms of pairs of quasitrees in associated embeddings. Surface meshes are frequent targets for DNA nanostructure self-assembly, and so we study both triangular and rectangular torus grids. We show that, aside from one exceptional family, a triangular torus grid contains an A-trail if and only if it has an odd number of vertices, and that such an A-trail is necessarily unknotted. On the other hand, while every rectangular torus grid contains an unknotted A-trail, we also show that any torus knot can be realized as an A-trail in some rectangular grid. Lastly, we use a gluing operation to construct infinite families of triangular and rectangular grids containing unknotted A-trails on surfaces of arbitrary genus. We also give infinite families of triangular grids containing no unknotted A-trail on surfaces of arbitrary nonzero genus.", "revisions": [ { "version": "v1", "updated": "2017-03-10T18:56:09.000Z" } ], "analyses": { "subjects": [ "05C10", "57M25", "05C45", "05C62" ], "keywords": [ "dna origami", "grids containing unknotted a-trails", "checkerboard-colorable torus graph", "rectangular grid", "infinite families" ], "note": { "typesetting": "TeX", "pages": 23, "language": "en", "license": "arXiv", "status": "editable" } } }