{ "id": "1503.08072", "version": "v1", "published": "2015-03-27T13:39:56.000Z", "updated": "2015-03-27T13:39:56.000Z", "title": "First-Passage of a Brownian Particle - Escape from a Bounded Potential", "authors": [ "Markus Nyberg", "Tobias Ambjörnsson", "Ludvig Lizana" ], "categories": [ "cond-mat.stat-mech" ], "abstract": "Many different processes depend on the first crossing of a boundary. For example, the time it takes for a protein find its target site on DNA, and the waiting time until a neurone starts firing. Motivated by the lack of tools accessible for computing first passage time densities (FPDTs) for general potentials, we propose a new method based on the Independent Interval Approximation (IIA). We generalise the IIA framework to non-smooth Brownian processes and derive a closed form expression for the FPDT in Laplace space for arbitrary boundary and starting point in one dimension. We apply our results to a Brownian particle in a harmonic potential and we find good agreement with Langevin dynamics simulations for one and two boundaries. We anticipate that our results will have a wide applicability an a number of escape problems.", "revisions": [ { "version": "v1", "updated": "2015-03-27T13:39:56.000Z" } ], "analyses": { "keywords": [ "brownian particle", "bounded potential", "first-passage", "computing first passage time densities", "independent interval approximation" ], "note": { "typesetting": "TeX", "pages": 0, "language": "en", "license": "arXiv", "status": "editable" } } }