{
  "id": "1502.06214",
  "version": "v1",
  "published": "2015-02-22T11:08:09.000Z",
  "updated": "2015-02-22T11:08:09.000Z",
  "title": "Hyperpolarized Nanodiamond with Long Spin Relaxation Times",
  "authors": [
    "Ewa Rej",
    "Torsten Gaebel",
    "Thomas Boele",
    "David E. J. Waddington",
    "David J. Reilly"
  ],
  "comment": "Supplemental Material available on request",
  "categories": [
    "cond-mat.mes-hall",
    "quant-ph"
  ],
  "abstract": "The use of hyperpolarized agents in magnetic resonance (MR), such as 13C-labeled compounds, enables powerful new imaging and detection modalities that stem from a 10,000-fold boost in signal. A major challenge for the future of the hyperpolarizaton technique is the inherently short spin relaxation times, typically < 60 seconds for 13C liquid-state compounds, which limit the time that the signal remains boosted. Here, we demonstrate that 1.1% natural abundance 13C spins in synthetic nanodiamond (ND) can be hyperpolarized at cryogenic and room temperature without the use of toxic free- radicals, and, owing to their solid-state environment, exhibit relaxation times exceeding 1 hour. Combined with the already established applications of NDs in the life-sciences as inexpensive fluorescent markers and non-cytotoxic substrates for gene and drug delivery, these results extend the theranostic capabilities of nanoscale diamonds into the domain of hyperpolarized MR.",
  "revisions": [
    {
      "version": "v1",
      "updated": "2015-02-22T11:08:09.000Z"
    }
  ],
  "analyses": {
    "keywords": [
      "long spin relaxation times",
      "hyperpolarized nanodiamond",
      "inherently short spin relaxation times",
      "natural abundance 13c spins",
      "13c liquid-state compounds"
    ],
    "publication": {
      "doi": "10.1038/ncomms9459",
      "journal": "Nature Communications",
      "year": 2015,
      "month": "Oct",
      "volume": 6,
      "pages": 8459
    },
    "note": {
      "typesetting": "TeX",
      "pages": 0,
      "language": "en",
      "license": "arXiv",
      "status": "editable",
      "adsabs": "2015NatCo...6E8459R"
    }
  }
}