{ "id": "1103.1923", "version": "v1", "published": "2011-03-10T00:37:59.000Z", "updated": "2011-03-10T00:37:59.000Z", "title": "Dengue disease, basic reproduction number and control", "authors": [ "Helena Sofia Rodrigues", "M. Teresa T. Monteiro", "Delfim F. M. Torres", "Alan Zinober" ], "comment": "This is a preprint of a paper whose final and definitive form has appeared in International Journal of Computer Mathematics (2011), DOI: 10.1080/00207160.2011.554540", "journal": "Int. J. Comput. Math. 89 (2012), no. 3, 334--346", "doi": "10.1080/00207160.2011.554540", "categories": [ "math.OC", "cs.SY", "physics.med-ph", "q-bio.OT" ], "abstract": "Dengue is one of the major international public health concerns. Although progress is underway, developing a vaccine against the disease is challenging. Thus, the main approach to fight the disease is vector control. A model for the transmission of Dengue disease is presented. It consists of eight mutually exclusive compartments representing the human and vector dynamics. It also includes a control parameter (insecticide) in order to fight the mosquito. The model presents three possible equilibria: two disease-free equilibria (DFE) and another endemic equilibrium. It has been proved that a DFE is locally asymptotically stable, whenever a certain epidemiological threshold, known as the basic reproduction number, is less than one. We show that if we apply a minimum level of insecticide, it is possible to maintain the basic reproduction number below unity. A case study, using data of the outbreak that occurred in 2009 in Cape Verde, is presented.", "revisions": [ { "version": "v1", "updated": "2011-03-10T00:37:59.000Z" } ], "analyses": { "subjects": [ "92B05", "93C95", "93D20" ], "keywords": [ "basic reproduction number", "dengue disease", "major international public health concerns", "equilibrium", "cape verde" ], "tags": [ "journal article" ], "note": { "typesetting": "TeX", "pages": 0, "language": "en", "license": "arXiv", "status": "editable", "adsabs": "2011arXiv1103.1923R" } } }